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Publications


Specification of the First Mammalian Cell Lineages In Vivo and In Vitro


Melanie D. White, Nicolas Plachta

Cold Spring Harbor Perspectives in Biology, vol. 12, 2019, pp. a035634


Expanding Actin Rings Zipper the Mouse Embryo for Blastocyst Formation


J. Zenker*, M. D. White*, M. Gasnier*, Y. D. Alvarez*, H. Y. G. Lim, S. Bissiere, M. Biro, N. Plachta

Cell, vol. 173, 2018, pp. 776-791 e17


Instructions for Assembling the Early Mammalian Embryo


M. D. White, J. Zenker, S. Bissiere, N. Plachta

Dev Cell, vol. 45, 2018, pp. 667-679


In Vivo Imaging of Single Mammalian Cells in Development and Disease


M. D. White, Z. W. Zhao, N. Plachta

Trends Mol Med, vol. 24, 2018, pp. 278-293


A microtubule-organizing center directing intracellular transport in the early mouse embryo


J. Zenker, M. D. White, R. M. Templin, R. G. Parton, O. Thorn-Seshold, S. Bissiere, N. Plachta

Science, vol. 357, 2017, pp. 925-928


How cells change shape and position in the early mammalian embryo


M. D. White, J. Zenker, S. Bissiere, N. Plachta

Curr Opin Cell Biol, vol. 44, 2017, pp. 7-13


Quantifying transcription factor-DNA binding in single cells in vivo with photoactivatable fluorescence correlation spectroscopy


Z. W. Zhao*, M. D. White*, Y. D. Alvarez*, J. Zenker, S. Bissiere, N. Plachta

Nat Protoc, vol. 12, 2017, pp. 1458-1471


Long-Lived Binding of Sox2 to DNA Predicts Cell Fate in the Four-Cell Mouse Embryo


M. D. White, J. F. Angiolini, Y. D. Alvarez, G. Kaur, Z. W. Zhao, E. Mocskos, L. Bruno, S. Bissiere, V. Levi, N. Plachta

Cell, vol. 165, 2016, pp. 75-87


Mouse Embryo Compaction


M. D. White, S. Bissiere, Y. D. Alvarez, N. Plachta

Curr Top Dev Biol, vol. 120, 2016, pp. 235-58


Quantitative imaging of mammalian transcriptional dynamics: from single cells to whole embryos


Z. W. Zhao, M. D. White, S. Bissiere, V. Levi, N. Plachta

BMC Biol, vol. 14, 2016, p. 115


Cortical Tension Allocates the First Inner Cells of the Mammalian Embryo


C. R. Samarage*, M. D. White*, Y. D. Alvarez*, J. C. Fierro-Gonzalez, Y. Henon, E. C. Jesudason, S. Bissiere, A. Fouras, N. Plachta

Dev Cell, vol. 34, 2015, pp. 435-47


How adhesion forms the early mammalian embryo


M. D. White, N. Plachta

Curr Top Dev Biol, vol. 112, 2015, pp. 1-17


The First Cell Fate Decision During Mammalian Development.


Nicolas. White Melanie D ; Plachta

David Warburton, Stem Cells, Tissue Engineering and Regenerative Medicine, World Scientific Publishing, Singapore, 2015, pp. 25-39


Cadherin-dependent filopodia control preimplantation embryo compaction


J. C. Fierro-Gonzalez*, M. D. White*, J. C. Silva, N. Plachta

Nat Cell Biol, vol. 15, 2013, pp. 1424-33


A Molecular Toolbox for Rapid Generation of Viral Vectors to Up- or Down-Regulate Neuronal Gene Expression in vivo


M. D. White, R. V. Milne, M. F. Nolan

Front Mol Neurosci, vol. 4, 2011, p. 8


RNAi for the treatment of prion disease: a window for intervention in neurodegeneration?


M. D. White, G. R. Mallucci

CNS Neurol Disord Drug Targets, vol. 8, 2009, pp. 342-52


Therapy for prion diseases: Insights from the use of RNA interference


M. D. White, G. R. Mallucci

Prion, vol. 3, 2009, pp. 121-8


Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease


M. D. White, M. Farmer, I. Mirabile, S. Brandner, J. Collinge, G. R. Mallucci

Proc Natl Acad Sci U S A, vol. 105, 2008, pp. 10238-43


Tuning of synaptic integration in the medial entorhinal cortex to the organization of grid cell firing fields


D. L. Garden, P. D. Dodson, C. O'Donnell, M. D. White, M. F. Nolan

Neuron, vol. 60, 2008, pp. 875-89


Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice


G. R. Mallucci, M. D. White, M. Farmer, A. Dickinson, H. Khatun, A. D. Powell, S. Brandner, J. G. Jefferys, J. Collinge

Neuron, vol. 53, 2007, pp. 325-35


Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma


Y. Zhang, N. I. Leaves, G. G. Anderson, C. P. Ponting, J. Broxholme, R. Holt, P. Edser, S. Bhattacharyya, A. Dunham, I. M. Adcock, L. Pulleyn, P. J. Barnes, J. I. Harper, G. Abecasis, L. Cardon, M. White, J. Burton, L. Matthews, R. Mott, M. Ross, R. Cox, M. F. Moffatt, W. O. Cookson

Nat Genet, vol. 34, 2003, pp. 181-6

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